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CompassR Yields Highly Organic‐Solvent‐Tolerant Enzymes through Recombination of Compatible Substitutions
In: Chemistry - a European journal, 27 (8), 2789-2797, 2020
[DOI: 10.1002/chem.202004471]

Cui, Haiyang
Jaeger, Karl-Erich
Davari, Mehdi D. (Corresponding author)
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
A peptide‐based coating toolbox to enable click chemistry on polymers, metals, and silicon through sortagging
In: Biotechnology & bioengineering, 118 (4), 1520-1530, 2021
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Nöth, Maximilian Wolfgang Stefan
Zou, Zhi
El-Awaad, Islam
De Lencastre Novaes, Leticia C.
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[Fachzeitschriftenartikel]
Rapid and Oriented Immobilization of Laccases on Electrodes via a Methionine-Rich Peptide
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Cui, Haiyang
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[Buchbeitrag]
Anchor peptides promote degradation of mixed plastics for recycling
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Ji, Yu
Lu, Yi
Puetz, Hendrik
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Understanding substrate binding and the role of gatekeeping residues in PigC access tunnels
In: Chemical communications, 57 (21), 2681-2684, 2021
[DOI: 10.1039/D0CC08226K]

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[Fachzeitschriftenartikel]
Directed Evolution of a Cp*RhIII‐Linked Biohybrid Catalyst Based on a Screening Platform with Affinity Purification
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Kato, Shunsuke
Onoda, Akira (Corresponding author)
Taniguchi, Naomasa
Schwaneberg, Ulrich
Hayashi, Takashi (Corresponding author)

[Fachzeitschriftenartikel]
A Photoclick‐Based High‐Throughput Screening for the Directed Evolution of Decarboxylase OleT
In: Chemistry - a European journal, 27 (3), 954-958, 2020
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[Fachzeitschriftenartikel]
Enzyme mimetic microgel coating for endogenous nitric oxide mediated inhibition of platelet activation
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[Buchbeitrag, Beitrag zu einem Tagungsband]
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Pariyar, S. (Corresponding author)
Jakob, Felix
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[Buchbeitrag]
Chapter Twelve - Machine learning-assisted enzyme engineering
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Siedhoff, Niklas Erik
Schwaneberg, Ulrich
Davari, Mehdi D. (Corresponding author)

[Fachzeitschriftenartikel]
Enzyme Hydration Determines Resistance in Organic Cosolvents
In: ACS catalysis, 10 (24), 14847-14856, 2020
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[Fachzeitschriftenartikel]
MicroGelzymes: pH-Independent Immobilization of Cytochrome P450 BM3 in Microgels
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Nöth, Maximilian Wolfgang Stefan
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[Fachzeitschriftenartikel]
Biocatalytic microgels (μ-Gelzymes) : synthesis, concepts, and emerging applications
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Nöth, Maximilian Wolfgang Stefan
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[Fachzeitschriftenartikel]
Designed Streptococcus pyogenes Sortase A Accepts Branched Amines as Nucleophiles in Sortagging
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Zou, Zhi
Nöth, Maximilian Wolfgang Stefan
Jakob, Felix
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Insights on intermolecular FMN-heme domain interaction and the role of linker length in cytochrome P450cin fusion proteins
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Belsare, Ketaki Deepak
Ruff, Anna Joelle
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Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Application cases of biological transformation in manufacturing technology
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Bergs, Thomas (Corresponding author)
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[Fachzeitschriftenartikel]
FhuA-Grubbs-Hoveyda Biohybrid Catalyst Embedded in a Polymer Film Enables Catalysis in Neat Substrates
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[Fachzeitschriftenartikel]
Incorporation of a Cp*Rh(III)-dithiophosphate Cofactor with Latent Activity into a Protein Scaffold Generates a Biohybrid Catalyst Promoting C(sp2)-H Bond Functionalization
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Kato, Shunsuke
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Grimm, Alexander Richard
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[Fachzeitschriftenartikel]
Enhancing Robustness of Sortase A by Loop Engineering and Backbone Cyclization
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Zou, Zhi
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Nöth, Maximilian Wolfgang Stefan
Jakob, Felix
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[Fachzeitschriftenartikel]
Display of functional nucleic acid polymerase on Escherichia coli surface and its application in directed polymerase evolution
In: Biotechnology & bioengineering, 17 (12), 3699-3711, 2020
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Chung, Mu‐En
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Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
KnowVolution of a GH5 Cellulase from Penicillium verruculosum to Improve Thermal Stability for Biomass Degradation
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Contreras Leiva, Francisca
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[Fachzeitschriftenartikel]
Enhancing Robustness of Sortase A by Loop Engineering and Backbone Cyclization
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Zou, Zhi
Mate, Diana M.
Nöth, Maximilian Wolfgang Stefan
Jakob, Felix
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
A colourimetric high-throughput screening system for directed evolution of prodigiosin ligase PigC
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[Fachzeitschriftenartikel]
Preparative-Scale Production of Testosterone Metabolites by Human Liver Cytochrome P450 Enzyme 3A4
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Fessner, Nico D.
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[Fachzeitschriftenartikel]
Loop engineering of aryl sulfotransferase B for improving catalytic performance in regioselective sulfation
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[Fachzeitschriftenartikel]
How to engineer organic solvent resistant enzymes : Insights from combined molecular dynamics and directed evolution study
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Cui, Haiyang
Stadtmüller, Tom Heinrich
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[Fachzeitschriftenartikel]
Engineered P450 BM3 and cpADH5 coupled cascade reaction for β-oxo fatty acid methyl ester production in whole cells
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Ensari, Yunus
de Almeida Santos, Gustavo
Ruff, Anna Joelle (Corresponding author)
Schwaneberg, Ulrich (Corresponding author)

[Buchbeitrag, Fachzeitschriftenartikel]
Effects of Proline Substitutions on the Thermostable LOV Domain from Chloroflexus aggregans
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[Fachzeitschriftenartikel]
Phytase-Based Phosphorus Recovery Process for 20 Distinct Press Cakes
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Herrmann, Kevin Rico
Ruff, Anna Joelle (Corresponding author)
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Directed evolution of VanR biosensor specificity in yeast
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[Buchbeitrag, Fachzeitschriftenartikel]
Engineering Robust Cellulases for Tailored Lignocellulosic Degradation Cocktails
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Contreras Leiva, Francisca
Pramanik, Subrata
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[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Activation of a Photoenzyme Results in Modified Structure and Dynamics
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Dataset to "An Enzymatic Route to α‐Tocopherol Synthons: Aromatic Hydroxylation of Pseudocumene and Mesitylene with P450 BM3", 2020
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[Dataset]
Dataset to "A hydroquinone-specific screening system for directed P450 evolution", 2020
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Schwaneberg, Ulrich
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[Fachzeitschriftenartikel]
Systematically Scrutinizing the Impact of Substitution Sites on Thermostability and Detergent Tolerance for Bacillus subtilis Lipase A
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Nutschel, Christina
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[Fachzeitschriftenartikel]
Advances in ultrahigh-throughput screening for directed enzyme evolution
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[Fachzeitschriftenartikel]
Engineering of Laccase CueO for Improved Electron Transfer in Bioelectrocatalysis by Semi-Rational Design
In: Chemistry - a European journal, 26 (22), 4974-4979, 2020
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Zhang, Lingling
Cui, Haiyang
Dhoke, Gaurao V.
Zou, Zhi
Sauer, Daniel Friedrich
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[Fachzeitschriftenartikel]
Matter-tag : A universal immobilization platform for enzymes on polymers, metals, and silicon-based materials
In: Biotechnology & bioengineering, 117 (1), 49-61, 2019
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Dedisch, Sarah
Wiens, Annika
Davari, Mehdi D.
Söder, Dominik
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[Fachzeitschriftenartikel]
Computer-Assisted Recombination (CompassR) Teaches us How to Recombine Beneficial Substitutions from Directed Evolution Campaigns
In: Chemistry - a European journal, 26 (3), 643-649, 2019
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Cui, Haiyang
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[Patent]
Pflanzenschutz- und/oder Pflanzenwachstumsförderungssystem, 2019

Jakob, Felix
Pich, Andrij
Rübsam, Kristin
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[Patent]
Verfahren zur Herstellung von Block-Polymeren mittels Verknüpfung von Blöcken durch eine Transpeptidase und Block-Polymere erhalten durch Transpeptidase-Verknüpfung, 2019

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Dai, Xiaolin
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[Patent]
Verwendung eines Polymers zur Steigerung der Reinigungsleistung eines protease-haltigen Wasch- oder Reinigungsmittels, 2019

Herbst, Daniela
Schulz, Alexander
Mussmann, Nina
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[Patent]
Leistungsverbesserte Varianten der alkalischen Protease aus B. lentus, 2019

Herbst, Daniela
Mussmann, Nina
Wieland, Susanne
Schwaneberg, Ulrich
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[Fachzeitschriftenartikel]
Directed Evolution of a Bacterial Laccase (CueO) for Enzymatic Biofuel Cells
In: Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker. International edition, 58 (14), 4562-4565, 2019
[DOI: 10.1002/anie.201814069]

Zhang, Lingling (Corresponding author)
Cui, Haiyang
Zou, Zhi
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[Dataset]
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Ruff, Anna Joëlle
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
A 96-multiplex capillary electrophoresis screening platform for product based evolution of P450 BM3
In: Scientific reports, 9, 15479, 2019
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Gärtner, Anna
Ruff, Anna Joelle
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Rapid and Robust Coating Method to Render Polydimethylsiloxane Surfaces Cell-Adhesive
In: ACS applied materials & interfaces, 11 (44), 41091-41099, 2019
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[Fachzeitschriftenartikel]
Critical effect of proline on thermostability of endoglucanase II from Penicillium verruculosum
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Dotsenko, Anna S. (Corresponding author)
Pramanik, Subrata
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[Fachzeitschriftenartikel]
A robust bacterial assay for high-throughput screening of human 4-hydroxyphenylpyruvate dioxygenase inhibitors
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Neuckermans, Jessie (Corresponding author)
Mertens, Alan
De Win, Dinja
Schwaneberg, Ulrich
De Kock, Joery (Corresponding author)

[Fachzeitschriftenartikel]
Selective Functionalization of Microgels with Enzymes by Sortagging
In: Bioconjugate chemistry, 30 (11), 2859-2869, 2019
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Zou, Zhi
Gau, Elisabeth
El-Awaad, Islam
Jakob, Felix
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[Fachzeitschriftenartikel]
Chemoenzymatic cascade for stilbene production from cinnamic acid catalyzed by ferulic acid decarboxylase and an artificial metathease
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[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Sustained crop protection by surface functionalization
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Langenbach, Caspar (Corresponding author)
Schwinges, Patrick
Jakob, Felix
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[Fachzeitschriftenartikel]
Consensus model of a cyanobacterial light-dependent protochlorophyllide oxidoreductase in its pigment-free apo-form and photoactive ternary complex
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[Buchbeitrag, Fachzeitschriftenartikel]
Ternary Complex Formation and Photoactivation of a Photoenzyme Results in Altered Protein Dynamics
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Stadler, Andreas Maximilian (Corresponding author)
Schneidewind, Judith
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[Fachzeitschriftenartikel]
Biadhesive Peptides for Assembling Stainless Steel and Compound Loaded Micro-Containers
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Apitius, Lina
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[Fachzeitschriftenartikel]
Biocatalyst Immobilization by Anchor Peptides on an Additively Manufacturable Material
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Büscher, Niclas
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Jakob, Felix
Schwaneberg, Ulrich (Corresponding author)
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[Fachzeitschriftenartikel]
In Situ Monitoring of Membrane Protein Insertion into Block Copolymer Vesicle Membranes and Their Spreading via Potential-Assisted Approach
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Mirzaei Garakani, Tayebeh
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[Fachzeitschriftenartikel]
Membrane-Mimetic Dendrimersomes Engulf Living Bacteria via Endocytosis
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Kostina, Nina Yu.
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[Buchbeitrag, Fachzeitschriftenartikel]
Directed Evolution of P450 BM3 towards Functionalization of Aromatic O-Heterocycles
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de Almeida Santos, Gustavo
Dhoke, Gaurao V.
Davari, Mehdi D.
Ruff, Anna Joelle
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Engineered phytases for emerging biotechnological applications beyond animal feeding
In: Applied microbiology and biotechnology, 103 (16), 6435-6448, 2019
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Herrmann, Kevin Rico
Ruff, Anna Joelle
Infanzón, Belén
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Rational surface engineering of an arginine deiminase (an antitumor enzyme) for increased PEGylation efficiency
In: Biotechnology & bioengineering, 116 (9), 2156-2166, 2019
[DOI: 10.1002/bit.27011]

Cheng, Feng
Yang, Jianhua
Schwaneberg, Ulrich
Zhu, Leilei (Corresponding author)

[Fachzeitschriftenartikel]
Turning a Killing Mechanism into an Adhesion and Antifouling Advantage
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Dedisch, Sarah (Corresponding author)
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[Fachzeitschriftenartikel]
One‐pot Two‐Step Chemoenzymatic Cascade for the Synthesis of a Bis‐benzofuran Derivative
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[Fachzeitschriftenartikel]
Depolymerization of Laccase-Oxidized Lignin in Aqueous Alkaline Solution at 37 °C
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Liu, Haifeng (Corresponding author)
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[Fachzeitschriftenartikel]
How To Engineer Ionic Liquids Resistant Enzymes : Insights from Combined Molecular Dynamics and Directed Evolution Study
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Pramanik, Subrata (Corresponding author)
Dhoke, Gaurao V.
Jaeger, Karl-Erich
Schwaneberg, Ulrich
Davari, Mehdi D.

[Fachzeitschriftenartikel]
Gerichtete Evolution ermöglicht das Design von maßgeschneiderten Proteinen zur nachhaltigen Produktion von Chemikalien und Pharmazeutika
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Bornscheuer, Uwe T.
Hauer, Bernhard
Jaeger, Karl Erich (Corresponding author)
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Auf dem Weg zur Evolution artifizieller Metalloenzyme - aus einem Protein‐Engineering‐Blickwinkel
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[Fachzeitschriftenartikel]
Ultrahigh-throughput screening system for directed polymer binding peptide evolution
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[Buchbeitrag, Fachzeitschriftenartikel]
Disulfide Bond Engineering of an Endoglucanase from Penicillium verruculosum to Improve Its Thermostability
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[Fachzeitschriftenartikel]
A thermostable flavin-based fluorescent protein from Chloroflexus aggregans : a framework for ultra-high resolution structural studies
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[Fachzeitschriftenartikel]
Chiral separation of d / l -arginine with whole cells through an engineered FhuA nanochannel
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[Fachzeitschriftenartikel]
Directed aryl sulfotransferase evolution toward improved sulfation stoichiometry on the example of catechols
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Anchor Peptide-Mediated Surface Immobilization of a Grubbs-Hoveyda-Type Catalyst for Ring-Opening Metathesis Polymerization
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[Fachzeitschriftenartikel]
Targeting microplastic particles in the void of diluted suspensions
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[Fachzeitschriftenartikel]
High Throughput Screening Method for Engineering P450 Towards Terminal Hydroxylation of Fatty Acids
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Directed Evolution Empowered Redesign of Natural Proteins for the Sustainable Production of Chemicals and Pharmaceuticals
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Bornscheuer, Uwe T.
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[Fachzeitschriftenartikel]
Towards the Evolution of Artificial Metalloenzymes - A Protein Engineer's Perspective
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[Fachzeitschriftenartikel]
A Semi-Rationally Engineered Bacterial Pyrrolysyl-tRNA Synthetase Genetically Encodes Phenyl Azide Chemistry
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[Fachzeitschriftenartikel]
A bifunctional dermaseptin-thanatin dipeptide functionalizes the crop surface for sustainable pest management
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[Fachzeitschriftenartikel]
Biohybrid catalysts for sequential one-pot reactions based on an engineered transmembrane protein
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[Fachzeitschriftenartikel]
Stimuli-Responsive Poly(N-Vinyllactams) with Glycidyl Side Groups: Synthesis, Characterization, and Conjugation with Enzymes
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[Patent]
Zellfreie Ultra-Hochdurchsatz-Durchmusterungssysteme für das Protein-Engineering, 2018

Schwaneberg, Ulrich
Vojcic, Ljubica
Körfer, Georgette Dorothea Johanna
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[Fachzeitschriftenartikel]
Theoretical Model of the Protochlorophyllide Oxidoreductase from a Hierarchy of Protocols
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[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Structural and biophysical studies of a LOV domain-derived fluorescent protein
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Nazarenko, V. V. (Corresponding author)
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Development of a Modular Biosensor System for Rapid Pathogen Detection
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Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones
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[Fachzeitschriftenartikel]
A hydroquinone-specific screening system for directed P450 evolution
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[Fachzeitschriftenartikel]
Directed OmniChange Evolution Converts P450 BM3 into an Alkyltrimethylammonium Hydroxylase
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[Fachzeitschriftenartikel]
Directed evolution of an acid Yersinia mollaretii phytase for broadened activity at neutral pH
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[Fachzeitschriftenartikel]
How to engineer glucose oxidase for mediated electron transfer
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[Fachzeitschriftenartikel]
Cyclotrimerization of phenylacetylene catalyzed by a cobalt half-sandwich complex embedded in an engineered variant of transmembrane protein FhuA
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[Fachzeitschriftenartikel]
Enzyme-Compatible Dynamic Nanoreactors from Electrostatically Bridged Like-Charged Surfactants and Polyelectrolytes
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[Fachzeitschriftenartikel]
Bestimmung der Stabilität und Enantioselektivität von Lipasen
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[Fachzeitschriftenartikel]
A Comparative Reengineering Study of cpADH5 through Iterative and Simultaneous Multisite Saturation Mutagenesis
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[Fachzeitschriftenartikel]
Loop engineering reveals the importance of active-site-decorating loops and gating residue in substrate affinity modulation of arginine deiminase (an anti-tumor enzyme)
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Schwaneberg, Ulrich
Zhu, Leilei (Corresponding author)

[Fachzeitschriftenartikel]
Unraveling the effects of amino acid substitutions enhancing lipase resistance to an ionic liquid: a molecular dynamics study
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[Fachzeitschriftenartikel]
Directed sortase A evolution for efficient site-specific bioconjugations in organic co-solvents
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[Fachzeitschriftenartikel]
Sortase-Mediated High-Throughput Screening Platform for Directed Enzyme Evolution
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[Fachzeitschriftenartikel]
Improved microscale cultivation of Pichia pastoris for clonal screening
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[Buchbeitrag, Fachzeitschriftenartikel]
Olefin metathesis catalysts embedded in β-barrel proteins: creating artificial metalloproteins for olefin metathesis
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Sauer, Daniel F. (Corresponding author)
Schiffels, Johannes
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Schwaneberg, Ulrich
Okuda, Jun (Corresponding author)

[Fachzeitschriftenartikel]
Enzyme-Polyelectrolyte Complexes Boost the Catalytic Performance of Enzymes
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[Fachzeitschriftenartikel]
Identification of Stable and Enantioselective Lipases for Biotechnological Applications
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Jaeger, Karl-Erich
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Pietruszka, Jörg
Kovacic, Filip (Corresponding author)

[Fachzeitschriftenartikel]
KnowVolution Campaign of an Aryl Sulfotransferase Increases Activity toward Cellobiose
In: Chemistry, 24 (64), 17117-17124, 2018
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[Fachzeitschriftenartikel]
Directed Evolution of Hyaluronic Acid Synthase from Pasteurella multocida towards High-Molecular-Weight Hyaluronic Acid
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[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Functionalizing plant surface for sustained plant protection
In: In vitro cellular & developmental biology / Plant, 54 (1 Supplement), O-132, 2018

Schwinges, Patrick (Corresponding author)
Pariyar, Shyam
Jakob, Felix
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[Fachzeitschriftenartikel]
KnowVolution of the Polymer-Binding Peptide LCI for Improved Polypropylene Binding
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Rübsam, Kristin
Davari, Mehdi D.
Jakob, Felix
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
A loop engineering strategy improves laccase lcc2 activity in ionic liquid and aqueous solution
In: Green chemistry, 20 (12), 2801-2812, 2018
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[Fachzeitschriftenartikel]
Comparison of Candida antarctica Lipase B Variants for Conversion of ε-Caprolactone in Aqueous Medium - Part 2
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[Fachzeitschriftenartikel]
Enzyme-Compatible Dynamic Nanoreactors from Electrostatically Bridged Like-charged Surfactants and Polyelectrolytes
In: Angewandte Chemie, 130 (30), 9546-9551, 2018
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Thiele, Martin J.
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[Fachzeitschriftenartikel]
Cavity Size Engineering of a β-Barrel Protein Generates Efficient Biohybrid Catalysts for Olefin Metathesis
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[Fachzeitschriftenartikel]
A Whole Cell E. coli Display Platform for Artificial Metalloenzymes: Poly(phenylacetylene) Production with a Rhodium-Nitrobindin Metalloprotein
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Sauer, Daniel F.
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[Fachzeitschriftenartikel]
Exploring the full natural diversity of single amino acid exchange reveals that 40-60% of BSLA positions improve organic solvents resistance
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[Buchbeitrag]
High-Throughput Screening Assays for Lipolytic Enzymes
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Fulton, Alexander (First author)
Hayes, Marc R.
Schwaneberg, Ulrich
Pietruszka, Jörg
Jaeger, Karl-Erich (Corresponding author)

[Fachzeitschriftenartikel]
Directed evolution of polypropylene and polystyrene binding peptides
In: Biotechnology and Bioengineering, 115 (2), 321-330, 2017
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Rübsam, Kristin (First author)
Weber, Lina (First author)
Jakob, Felix
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Selecting of a cytochrome P450 cam SeSaM library with 3-chloroindole and endosulfan : Identification of mutants that dehalogenate 3-chloroindole
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[Buchbeitrag, Fachzeitschriftenartikel]
Crystallographic insights into a cobalt (III) sepulchrate based alternative cofactor system of P450 BM3 monooxygenase
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Panneerselvam, Saravanan (First author)
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[Patent]
Glucose oxidase variants and methods of using the same, 2018

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[Patent]
Verfahren und Materialien zur Manipulation von Nukleinsäuren, 2017

Häfner, Stefan
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Dennig, Alexander
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[Patent]
Poröse Dünnschichtmembran, Verfahren zu ihrer Herstellung sowie Verwendungsmöglichkeiten, 2017

Charan, Himanshi
Glebe, Ulrich
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[Poster]
Bifunctional Fusion Proteins for Plant Protection - BiFuProts -
In: 4. BioSC Forum Köln 2017-11-27 - 2017-11-27, 2017

Schwinges, Patrick (First author)
Jakob, Felix
Rahimi, Mehran
Schwaneberg, Ulrich
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[Fachzeitschriftenartikel]
Engineering Enhanced Pore Sizes Using FhuA Δ1-160 from E. coli Outer Membrane as Template
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Liu, Zhanzhi (First author)
Ghai, Ishan
Winterhalter, Mathias (Corresponding author)
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Electron transfer pathways in a light, oxygen, voltage (LOV) protein devoid of the photoactive cysteine
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[Fachzeitschriftenartikel]
An enzymatic route to α-tocopherol synthons: Aromatic hydroxylation of pseudocumene and mesitylene with P450 BM3
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Dennig, Alexander (Corresponding author)
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[Fachzeitschriftenartikel]
Recombinant RNA Polymerase from Geobacillus sp. GHH01 as tool for rapid generation of metagenomic RNAs using in vitro technologies
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[Fachzeitschriftenartikel]
Inversion of cpADH5 Enantiopreference and Altered Chain Length Specificity for Methyl 3-Hydroxyalkanoates
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Ensari, Yunus (First author)
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[Fachzeitschriftenartikel]
Sortase-Mediated Surface Functionalization of Stimuli-Responsive Microgels
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[Fachzeitschriftenartikel]
2-Methyl-2,4-pentanediol (MPD) boosts as detergent-substitute the performance of ß-barrel hybrid catalyst for phenylacetylene polymerization
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[Fachzeitschriftenartikel]
Biofunctional Microgel-Based Fertilizers for Controlled Foliar Delivery of Nutrients to Plants
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[Fachzeitschriftenartikel]
Multi-step biocatalytic depolymerization of lignin
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Picart, Pere (First author)
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[Fachzeitschriftenartikel]
Biofunktionale Mikrogel-basierte Dünger zur kontrollierten Blattdüngung mit Nährstoffen auf Pflanzen
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[Buchbeitrag, Fachzeitschriftenartikel]
Are Directed Evolution Approaches Efficient in Exploring Nature’s Potential to Stabilize a Lipase in Organic Cosolvents?
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[Fachzeitschriftenartikel]
Sugar-Improved Enzymatic Synthesis of Biodiesel with Yarrowia lipolytica Lipase 2
In: Energy & fuels, 31 (6), 6248-6256, 2017
[DOI: 10.1021/acs.energyfuels.7b01091]

Cao, Hao
Wang, Meng
Deng, Li
Liu, Luo
Schwaneberg, Ulrich
et al.

[Fachzeitschriftenartikel]
Casting epPCR (cepPCR): A simple random mutagenesis method to generate high quality mutant libraries
In: Biotechnology & bioengineering, 114 (9), 1921-1927, 2017
[DOI: 10.1002/bit.26327]

Yang, Jianhua
Ruff, Anna Joelle
Arlt, Marcus
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Anchor peptides: A green and versatile method for polypropylene functionalization
In: Polymer : the international journal for the science and technology of polymers, 116, 124-132, 2017
[DOI: 10.1016/j.polymer.2017.03.070]

Rübsam, Kristin (First author)
Stomps, Benjamin
Böker, Alexander
Jakob, Felix
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Nano-thin walled micro-compartments from transmembrane protein-polymer conjugates
In: Soft matter, 13 (15), 2866-2875, 2017
[DOI: 10.1039/C6SM02520J]

Charan, Himanshu
Glebe, Ulrich
Anand, Deepak
Kinzel, Julia
Zhu, Leilei
et al.

[Buchbeitrag]
Recent Advances in Directed Phytase Evolution and Rational Phytase Engineering
In: Directed Enzyme Evolution: Advances and Applications / Miguel Alcalde Editor, 145-172, 2017
[DOI: 10.1007/978-3-319-50413-1_6]

Shivange, Amol V. (Corresponding author)
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Amino acid substitutions in random mutagenesis libraries: lessons from analyzing 3000 mutations
In: Applied microbiology and biotechnology, 101 (8), 3177-3187, 2017
[DOI: 10.1007/s00253-016-8035-1]

Zhao, Jing
Frauenkron-Machedjou, Victorine Josiane
Kardashliev, Tsvetan
Ruff, Anna Joelle
Zhu, Leilei
et al.

[Fachzeitschriftenartikel]
Cellulolytic RoboLector - towards an automated high-throughput screening platform for recombinant cellulase expression
In: Journal of biological engineering : jbe, 11 (1), 1-18, 2017
[DOI: 10.1186/s13036-016-0043-2]

Mühlmann, Martina Julia
Kunze, Martin
Ribeiro, Joaquim
Geinitz, Bertram Michael
Lehmann, Christian
et al.

[Fachzeitschriftenartikel]
Novel technique for high throughput measurement of active monooxygenase concentration
In: Biotechnology and Bioengineering, 114 (4), 929-933, 2016
[DOI: 10.1002/bit.26215]

Welters, Tim (First author)
Horn, Thomas
Ruff, Anna Joelle
Schwaneberg, Ulrich
Büchs, Jochen (Corresponding author)

[Poster]
Bifunctional Fusion Proteins for Plant Protection - BiFuProts -
In: 1. PhD Day NRW - "Future Bioeconomy" Düsseldorf 2016-09-22 - 2016-09-22, 2016

Schwinges, Patrick (First author)
Jakob, Felix
Rahimi, Mehran
Schwaneberg, Ulrich
Schwarz, Christian
et al.

[Poster]
Bifunctional Fusion Proteins for Plant Protection - BiFuProts -
In: 29. Conference Molecular Biology of Plants Dabringhausen 2016-02-23 - 2016-02-26, 2016

Schwinges, Patrick
Jakob, Felix
Rahimi, Mehran
Schwaneberg, Ulrich
Schwarz, Christian
et al.

[Konferenzbeitrag]
Bifunctional Fusion Proteins for Plant Protection
In: Tagung der DPG-Arbeitskreise "Mykologie" und "Wirt-Parasit-Beziehungen Gießen 2016-03-17 - 2016-03-18, 2016

Schwinges, Patrick (First author)
Jakob, Felix
Rahimi, Mehran
Schwaneberg, Ulrich
Schwarz, Christian
et al.

[Poster]
Bifunctional Fusion Proteins for Plant Protection
In: 3. BioSC-Forum Köln 2016-11-22 - 2016-11-22, 2016

Schwaneberg, Ulrich (Corresponding author)
Jakob, Felix
Conrath, Uwe
Langenbach, Caspar
Schmitt, Lutz
et al.

[Fachzeitschriftenartikel]
Directed evolution of P450cin for mediated electron transfer
In: Protein engineering design and selection, 30 (2), 119-127, 2016
[DOI: 10.1093/protein/gzw072]

Belsare, Ketaki D.
Horn, Thomas
Ruff, Anna Joëlle
Martinez, Ronny
Magnusson, Anders
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[Fachzeitschriftenartikel]
Protein consensus-based surface engineering (ProCoS): a computer-assisted method for directed protein evolution
In: BioTechniques : the international journal of life science methods, 61 (6), 305-314, 2016
[DOI: 10.2144/000114483]

Shivange, Amol V. (Corresponding author)
Hoeffken, Hans Wolfgang
Haefner, Stefan
Schwaneberg, Ulrich

[Buchbeitrag, Fachzeitschriftenartikel]
An engineered outer membrane pore enables an efficient oxygenation of aromatics and terpenes
In: Journal of molecular catalysis / B, 134 (Part B), 285-294, 2016
[DOI: 10.1016/j.molcatb.2016.11.007]

Ruff, Anna Joelle (First author)
Arlt, Marcus (First author)
van Ohlen, Maike
Kardashliev, Tsvetan
Konarzycka-Bessler, Monika
et al.

[Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Screening through the PLICable promoter toolbox enhances protein production in Escherichia coli
In: Biotechnology journal : BTJ, 11 (12), 1639-1647, 2016
[DOI: 10.1002/biot.201600270]

Yang, Jianhua (First author)
Ruff, Anna Joelle
Hamer, Stefanie Nicole
Cheng, Feng
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
A whole cell biocatalyst for double oxidation of cyclooctane
In: Journal of industrial microbiology & biotechnology, 43 (12), 1641-1646, 2016
[DOI: 10.1007/s10295-016-1844-5]

Müller, Christina Andrea (First author)
Weingartner, Alexandra Maria (First author)
Dennig, Alexander
Ruff, Anna Joelle
Gröger, H.
et al.

[Buchbeitrag, Fachzeitschriftenartikel]
CaLB Catalyzed Conversion of ε-Caprolactone in Aqueous Medium : Part 1: Immobilization of CaLB to Microgels
In: Polymers, 8 (10), 372, 2016
[DOI: 10.3390/polym8100372]

Engel, Stefan
Höck, Heidi
Bocola, Marco
Keul, Helmut
Schwaneberg, Ulrich
et al.

[Buchbeitrag]
Engineering Proteases for Industrial Applications
In: Applied biocatalysis : from fundamental science to industrial applications / edited by Lutz Hilterhaus, Andreas Liese, Ulrich Kettling, and Garabed Antranikian, 101-120, 2016
[DOI: 10.1002/9783527677122.ch6]

Vojcic, Ljubica (First author)
Jakob, Felix (First author)
Martinez, Ronny
Hellmuth, Hendrik
O'Connell, Timothy
et al.

[Fachzeitschriftenartikel]
Tunable Enzymatic Activity and Enhanced Stability of Cellulase Immobilized in Biohybrid Nanogels
In: Biomacromolecules, 17 (11), 3619-3631, 2016
[DOI: 10.1021/acs.biomac.6b01119]

Peng, Huan
Rübsam, Kristin
Jakob, Felix
Schwaneberg, Ulrich
Pich, Andrij (Corresponding author)

[Fachzeitschriftenartikel]
Reactive Copolymers Based on N-Vinyl Lactams with Pyridyl Disulfide Side Groups via RAFT Polymerization and Postmodification via Thiol-Disulfide Exchange Reaction
In: Macromolecules : web edition, 49 (19), 7141-7154, 2016
[DOI: 10.1021/acs.macromol.6b01210]

Peng, Huan
Rübsam, Kristin
Huang, Xiaobin
Jakob, Felix
Karperien, Marcel
et al.

[Fachzeitschriftenartikel]
Reversible Deactivation of Enzymes by Redox-Responsive Nanogel Carriers
In: Macromolecular rapid communications, 37 (21), 1765-1771, 2016
[DOI: 10.1002/marc.201600476]

Peng, Huan
Rübsam, Kristin
Jakob, Felix
Pazdzior, Patrizia
Schwaneberg, Ulrich
et al.

[Patent]
Plant Protection and/or Plant Growth Promotion System, 2016

Conrath, Uwe
Jakob, Felix
Pich, Andrij
Rübsam, Kristin
Schwaneberg, Ulrich
et al.

[Fachzeitschriftenartikel]
Grafting PNIPAAm from ß-barrel shaped transmembrane nanopores
In: Biomaterials : biomaterials reviews online, 107, 115-123, 2016
[DOI: 10.1016/j.biomaterials.2016.08.033]

Charan, Himanshu (First author)
Kinzel, Julia (First author)
Glebe, Ulrich
Anand, Deepak
Garakani, Tayebeh Mirzaei
et al.

[Fachzeitschriftenartikel]
Wie Enzym-Engineering das Waschen optimiert
In: Naturwissenschaften im Unterricht / Chemie, 152, 44-48, 2016

Jakob, Felix
Musset, Andrea
Kremer, Kerstin
Schwaneberg, Ulrich

[Abstract, Buchbeitrag, Beitrag zu einem Tagungsband]
Phytoalexine und bifunktionale Fusionsproteine für den Pflanzenschutz
In: 60. Deutsche Pflanzenschutztagung : 20. - 23. September 2016, Martin-Luther-Universität Halle-Wittenberg ; Kurzfassungen der Beiträge / Julius-Kühn-Institut, Bundesforschungsinstitut für Kulturpflanzen, 2016

Langenbach, Caspar
Beyer, Sebastian Felix
Schwinges, Patrick
Jakob, Felix
Rahimi, Mehran
et al.

[Fachzeitschriftenartikel]
What’s My Substrate? Computational Function Assignment of Candida parapsilosis ADH5 by Genome Database Search, Virtual Screening, and QM/MM Calculations
In: Journal of chemical information and modeling, 56 (7), 1313-1323, 2016
[DOI: 10.1021/acs.jcim.6b00076]

Dhoke, Gaurao V.
Ensari, Yunus
Davari, Mehdi D.
Ruff, Anna Joëlle
Schwaneberg, Ulrich
et al.

[Fachzeitschriftenartikel]
Artificial Diels-Alderase based on the transmembrane protein FhuA
In: Beilstein journal of organic chemistry, 12, 1314-1321, 2016
[DOI: 10.3762/bjoc.12.124]

Osseili, Hassan
Sauer, Daniel F.
Beckerle, Klaus
Arlt, Marcus
Himiyama, Tomoki
et al.

[Fachzeitschriftenartikel]
Reporter Immobilization Assay (REIA) for Bioconjugating Reactions
In: Bioconjugate chemistry, 27 (6), 1484-1492, 2016
[DOI: 10.1021/acs.bioconjchem.6b00111]

Schatte, Martin (Corresponding author)
Bocola, Marco
Roth, Teresa
Martinez, Ronny
Kopetzki, Erhard
et al.

[Fachzeitschriftenartikel]
In vitro flow cytometry-based screening platform for cellulase engineering
In: Scientific reports, 6, 26128, 2016
[DOI: 10.1038/srep26128]

Körfer, Georgette Dorothea Johanna
Pitzler, Christian
Vojcic, Ljubica
Martinez, Ronny
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Photophysics of the LOV-Based Fluorescent Protein Variant iLOV-Q489K Determined by Simulation and Experiment
In: The journal of physical chemistry / B, 120 (13), 3344-3352, 2016
[DOI: 10.1021/acs.jpcb.6b01512]

Davari, Mehdi D. (Corresponding author)
Kopka, Benita
Wingen, Marcus
Bocola, Marco
Drepper, Thomas
et al.

[Fachzeitschriftenartikel]
Substrate thiophosphorylation by Arabidopsis mitogen-activated protein kinases
In: BMC plant biology, 16 (48), 48, 2016
[DOI: 10.1186/s12870-016-0731-6]

Leißing, Franz Josef
Nomoto, Mika
Bocola, Marco
Schwaneberg, Ulrich
Tada, Yasuomi
et al.

[Fachzeitschriftenartikel]
Unraveling Binding Effects of Cobalt(II) Sepulchrate with the Monooxygenase P450 BM-3 Heme Domain Using Molecular Dynamics Simulations
In: Journal of chemical theory and computation, 12 (1), 353-363, 2015
[DOI: 10.1021/acs.jctc.5b00290]

Verma, Rajni
Schwaneberg, Ulrich
Holtmann, Dirk
Roccatano, Danilo (Corresponding author)

[Fachzeitschriftenartikel]
Iterative key-residues interrogation of a phytase with thermostability increasing substitutions identified in directed evolution
In: Applied microbiology and biotechnology, 100 (1), 227-242, 2015
[DOI: 10.1007/s00253-015-6959-5]

Shivange, Amol V.
Roccatano, Danilo
Schwaneberg, Ulrich (Corresponding author)

[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Efficient phosphate recovery from agro waste streams by enzyme, strain, and process engineering
In: Yeast, 32, S167-S167, 2015

Ruff, Anna Joelle
Hamer, Stephanie
Förster, Jan
Blank, Lars M.
Schwaneberg, Ulrich

[Patent]
Stabilized Inhibitor Protease Variants, 2015

Hellmuth, Hendrik
Laufs, Brian
Aydemir, Ayhan
Weber, Thomas
O'Connell, Timothy
et al.

[Fachzeitschriftenartikel]
Correction: A flow cytometer-based whole cell screening toolbox for directed hydrolase evolution through fluorescent hydrogels
In: Chemical communications, 51 (98), 17483-17483, 2015
[DOI: 10.1039/C5CC90528A]

Lülsdorf, Nina
Pitzler, Christian
Biggel, Michael
Martinez, Ronny
Vojcic, Ljubica
et al.

[Fachzeitschriftenartikel]
A Highly Active Biohybrid Catalyst for Olefin Metathesis in Water: Impact of a Hydrophobic Cavity in a β-Barrel Protein
In: ACS catalysis, 5 (12), 7519-7522, 2015
[DOI: 10.1021/acscatal.5b01792]

Sauer, Daniel F.
Himiyama, Tomoki
Tachikawa, Kengo
Fukumoto, Kazuki
Onoda, Akira
et al.

[Fachzeitschriftenartikel]
Activity prediction of substrates in NADH-dependent carbonyl reductase by docking requires catalytic constraints and charge parameterization of catalytic zinc environment
In: Journal of computer aided molecular design, 29 (11), 1057-1069, 2015
[DOI: 10.1007/s10822-015-9878-8]

Dhoke, Gaurao V.
Loderer, Christoph
Davari, Mehdi D.
Ansorge-Schumacher, Marion B.
Schwaneberg, Ulrich
et al.

[Fachzeitschriftenartikel]
Light-induced structural changes in a short light, oxygen, voltage (LOV) protein revealed by molecular dynamics simulations : implications for the understanding of LOV photoactivation
In: Frontiers in molecular biosciences, 2, 1-17, 2015
[DOI: 10.3389/fmolb.2015.00055]

Bocola, Marco (Corresponding author)
Schwaneberg, Ulrich
Jaeger, Karl-Erich
Krauss, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Ionic liquid activated Bacillus subtilis lipase A variants through cooperative surface substitutions
In: Biotechnology & bioengineering, 112 (10), 1997-2004, 2015
[DOI: 10.1002/bit.25617]

Zhao, Jing
Jia, Ning
Jaeger, Karl-Erich
Bocola, Marco
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Water-Soluble Reactive Copolymers Based on Cyclic N -Vinylamides with Succinimide Side Groups for Bioconjugation with Proteins
In: Macromolecules, 48 (13), 4256-4268, 2015
[DOI: 10.1021/acs.macromol.5b00947]

Peng, Huan
Kather, Michael
Rübsam, Kristin
Jakob, Felix
Schwaneberg, Ulrich
et al.

[Fachzeitschriftenartikel]
Investigation of Structural Determinants for the Substrate Specificity in the Zinc-Dependent Alcohol Dehydrogenase CPCR2 from Candida parapsilosis
In: ChemBioChem, 16 (10), 1512-1519, 2015
[DOI: 10.1002/cbic.201500100]

Loderer, Christoph
Dhoke, Gaurao V.
Davari, Mehdi D.
Kroutil, Wolfgang
Schwaneberg, Ulrich
et al.

[Buchbeitrag, Fachzeitschriftenartikel]
Hybrid Ruthenium ROMP Catalysts Based on an Engineered Variant of β-Barrel Protein FhuA ΔCVF tev : Effect of Spacer Length
In: Chemistry, 10 (1), 177-182, 2015
[DOI: 10.1002/asia.201403005]

Sauer, Daniel F.
Bocola, Marco
Broglia, Claudio
Arlt, Marcus
Zhu, Leilei
et al.

[Fachzeitschriftenartikel]
Combinatorial optimization of synthetic operons for the microbial production of p-coumaryl alcohol with Escherichia coli
In: Microbial cell factories, 14, 79, 2015
[DOI: 10.1186/s12934-015-0274-9]

van Summeren-Wesenhagen, Philana V.
Voges, Raphael
Dennig, Alexander
Sokolowsky, Sascha
Noack, Stephan
et al.

[Fachzeitschriftenartikel]
A first continuous 4-aminoantipyrine (4-AAP)-based screening system for directed esterase evolution
In: Applied microbiology and biotechnology, 99 (12), 5237-5246, 2015
[DOI: 10.1007/s00253-015-6612-3]

Lülsdorf, Nina
Vojcic, Ljubica
Hellmuth, Hendrik
Weber, Thomas T.
Mußmann, Nina
et al.

[Fachzeitschriftenartikel]
Directed evolution 2.0 : improving and deciphering enzyme properties
In: Chemical communications, 51, 9760-9772, 2015
[DOI: 10.1039/C5CC01594D]

Cheng, Feng
Zhu, Leilei
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
QM/MM Calculations Revealing the Resting and Catalytic States in Zinc-Dependent Medium-Chain Dehydrogenases/Reductases
In: ACS catalysis, 5, 3207-3215, 2015
[DOI: 10.1021/cs501524k]

Dhoke, Gaurao V.
Davari, Mehdi D.
Schwaneberg, Ulrich
Bocola, Marco (Corresponding author)

[Fachzeitschriftenartikel]
A flow cytometer-based whole cell screening toolbox for directed hydrolase evolution through fluorescent hydrogels
In: Chemical communications, 51, 8679-8682, 2015
[DOI: 10.1039/C5CC01791B]

Lülsdorf, Nina
Pitzler, Christian
Biggel, Michael
Martinez, Ronny
Vojcic, Ljubica
et al.

[Fachzeitschriftenartikel]
Exploring the Protein Stability Landscape : Bacillus subtilis Lipase A as a Model for Detergent Tolerance
In: ChemBioChem, 16, 930-936, 2015
[DOI: 10.1002/cbic.201402664]

Fulton, Alexander
Frauenkron-Machedjou, Victorine Josiane
Skoczinski, Pia
Wilhelm, Susanne
Zhu, Leilei
et al.

[Fachzeitschriftenartikel]
Towards Understanding Directed Evolution : more than Half of All Amino Acid Positions Contribute to Ionic Liquid Resistance of Bacillus subtilis Lipase A
In: ChemBioChem, 16, 937-945, 2015
[DOI: 10.1002/cbic.201402682]

Frauenkron-Machedjou, Victorine Josiane
Fulton, Alexander
Zhu, Leilei
Anker, Carolin
Bocola, Marco
et al.

[Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Advances in protease engineering for laundry detergents
In: New biotechnology, 32 (6), 629-634, 2015
[DOI: 10.1016/j.nbt.2014.12.010]

Vojcic, Ljubica
Pitzler, Christian
Körfer, Georgette
Jakob, Felix
Martinez, Ronny
et al.

[Fachzeitschriftenartikel]
A competitive flow cytometry screening system for directed evolution of therapeutic enzyme
In: ACS synthetic biology, 4 (7), 768-775, 2015
[DOI: 10.1021/sb500343g]

Cheng, Feng
Kardashliev, Tsvetan
Pitzler, Christian
Shehzad, Aamir
Lue, Hongqi
et al.

[Fachzeitschriftenartikel]
Directed arginine deiminase evolution for efficient inhibition of arginine-auxotrophic melanomas
In: Applied microbiology and biotechnology, 99 (3), 1237-1247, 2015
[DOI: 10.1007/s00253-014-5985-z]

Cheng, Feng (Corresponding author)
Zhu, Leilei (Corresponding author)
Lue, Hongqi
Bernhagen, Jürgen
Schwaneberg, Ulrich (Corresponding author)

[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Development of a flow cytometer-based in vitro compartmentalization screening platform for directed protein evolution
In: New biotechnology, 31 (Supplement), PI-18, 2014
[DOI: 10.1016/j.nbt.2014.05.1987]

Wirtz, Georgette (Corresponding author)
Pitzler, Christian
Vojcic, Ljubica
Martinez, Ronny
Schwaneberg, Ulrich

[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Lessons on directed evolution of hydrolases and glucose oxidase
In: New biotechnology, 31 (Supplement), O4-5, 2014
[DOI: 10.1016/j.nbt.2014.05.1658]

Schwaneberg, Ulrich

[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
A fluorescent polymer shell-based enzyme screening platform for hydrolases using flow cytometry
In: New biotechnology, 31 (Supplement), PI-19, 2014
[DOI: 10.1016/j.nbt.2014.05.1988]

Pitzler, Christian (Corresponding author)
Wirtz, Georgette
Vojcic, Ljubica
Hiltl, Stephanie
Böker, Alexander
et al.

[Fachzeitschriftenartikel]
A fluorescent hydrogel-based flow cytometry screening platform for hydrolytic enzymes
In: Chemistry & Biology, 21 (12), 1733-1742, 2014
[DOI: 10.1016/j.chembiol.2014.10.018]

Pitzler, Christian
Wirtz, Georgette
Vojcic, Ljubica
Hiltl, Stephanie
Böker, Alexander
et al.

[Fachzeitschriftenartikel]
Mediated electron transfer with monooxygenases-Insight in interactions between reduced mediators and the co-substrate oxygen
In: Journal of molecular catalysis / B, Enzymatic, 108, 51-58, 2014
[DOI: 10.1016/j.molcatb.2014.06.011]

Tosstorff, Andreas
Dennig, Alexander
Ruff, Anna Joëlle
Schwaneberg, Ulrich
Sieber, Volker
et al.

[Fachzeitschriftenartikel]
Engineering of Highly Selective Variants of Parvibaculum lavamentivorans Alcohol Dehydrogenase
In: ChemBioChem, 15 (14), 2050-2052, 2014
[DOI: 10.1002/cbic.201402216]

Spickermann, Dominik
Hausmann, Sascha
Degering, Christian
Schwaneberg, Ulrich
Leggewie, Christian (Corresponding author)

[Buchbeitrag]
The Mutagenesis Assistant Program
In: Directed evolution library creation : methods and protocols / ed. by Elizabeth M. J. Gillam ..., 279-290, 2014
[DOI: 10.1007/978-1-4939-1053-3_19]

Verma, Rajni
Wong, Tuck Seng
Schwaneberg, Ulrich
Roccatano, Danilo (Corresponding author)

[Buchbeitrag]
The Sequence Saturation Mutagenesis (SeSaM) Method
In: Directed evolution library creation : methods and protocols / ed. by Elizabeth M. J. Gillam ..., 45-68, 2014
[DOI: 10.1007/978-1-4939-1053-3_4]

Ruff, Anna Joëlle
Kardashliev, Tsvetan
Dennig, Alexander
Schwaneberg, Ulrich (Corresponding author)

[Buchbeitrag]
OmniChange : Simultaneous Site Saturation of Up to Five Codons
In: Directed evolution library creation : methods and protocols / ed. by Elizabeth M. J. Gillam ..., 139-149, 2014
[DOI: 10.1007/978-1-4939-1053-3_9]

Dennig, Alexander
Marienhagen, Jan
Ruff, Anna Joëlle
Schwaneberg, Ulrich (Corresponding author)

[Buchbeitrag, Fachzeitschriftenartikel]
Whole-cell double oxidation of n-heptane
In: Journal of biotechnology, 191, 196-204, 2014
[DOI: 10.1016/j.jbiotec.2014.06.001]

Müller, Christina Andrea
Dennig, Alexander
Welter, Tim
Winkler, Till
Ruff, Anna Joëlle
et al.

[Fachzeitschriftenartikel]
Lessons from diversity of directed evolution experiments by an analysis of 3,000 mutations
In: Biotechnology and bioengineering (12), 10 S., 2014
[DOI: 10.1002/bit.25302]

Zhao, Jing
Kardashliev, Tsvetan
Ruff, Anna Joëlle
Bocola, Marco
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
P-Link: A method for generating multicomponent cytochrome P450 fusions with variable linker length
In: BioTechniques, 57 (1), 13-20, 2014
[DOI: 10.2144/000114187]

Belsare, Ketaki D.
Ruff, Anna Joëlle
Martinez, Ronny
Shivange, Amol V.
Mundhada, Hemanshu
et al.

[Fachzeitschriftenartikel]
PTEN-inhibition by zinc ions augments interleukin-2-mediated Akt phosphorylation
In: Metallomics : integrated biometal science, 6 (7), 1277-1287, 2014
[DOI: 10.1039/c3mt00197k]

Plum, Laura Marie
Brieger, Anne
Engelhardt, Gabriela
Hebel, Silke
Nessel, Andreas
et al.

[Fachzeitschriftenartikel]
Ionic liquid and deep eutectic solvent-activated CelA2 variants generated by directed evolution
In: Applied microbiology and biotechnology, 98 (12), 5775-5785, 2014
[DOI: 10.1007/s00253-014-5771-y]

Lehmann, Christian
Bocola, Marco
Streit, Wolfgang R.
Martinez, Ronny
Schwaneberg, Ulrich (Corresponding author)

[Buchbeitrag, Fachzeitschriftenartikel]
Alcohol dehydrogenase stabilization by additives under industrially relevant reaction conditions
In: Journal of molecular catalysis / B, Enzymatic, 103 (SI), 24-28, 2014
[DOI: 10.1016/j.molcatb.2013.11.015]

Spickermann, Dominik
Kara, Selin
Barackov, Ivana
Hollmann, Frank
Schwaneberg, Ulrich
et al.

[Fachzeitschriftenartikel]
Rhodium-Complex-Linked Hybrid Biocatalyst: Stereo-Controlled Phenylacetylene Polymerization within an Engineered Protein Cavity
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Extending the substrate scope of a Baeyer-Villiger monooxygenase by multiple-site mutagenesis
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A High-Throughput Screening Method to Reengineer DNA Polymerases for Random Mutagenesis
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Protein Engineering of the Antitumor Enzyme PpADI for Improved Thermal Resistance
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[Fachzeitschriftenartikel]
Insights on activity and stability of subtilisin E towards guanidinium chloride and sodium dodecylsulfate
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Multi-site saturation by OmniChange yields a pH- and thermally improved phytase
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[Fachzeitschriftenartikel]
Insight into the Redox Partner Interaction Mechanism in Cytochrome P450BM-3 Using Molecular Dynamics Simulations
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[Patent]
Stereoselective hydroxylation of benzenes, 2013

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Martinez, Ronny (Corresponding author)
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Increasing protein production by directed vector backbone evolution
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[Fachzeitschriftenartikel]
A Hybrid Ring-Opening Metathesis Polymerization Catalyst Based on an Engineered Variant of the b-Barrel Protein FhuA
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[Fachzeitschriftenartikel]
Benzylic hydroxylation of aromatic compounds by P450 BM3
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Surface charge engineering of a Bacillus gibsonii subtilisin protease
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[Fachzeitschriftenartikel]
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In Vitro Double Oxidation of n-Heptane with Direct Cofactor Regeneration
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P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation
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Verma, Rajni
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Roccatano, Danilo (Corresponding author)

[Fachzeitschriftenartikel]
Increasing activity and thermal resistance of Bacillus gibsonii alkaline protease (BgAP) by directed evolution
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Reengineered carbonyl reductase for reducing methyl-substituted cyclohexanones
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Reengineering of subtilisin Carlsberg for oxidative resistance
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Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water
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Durchflusszytometrie zum Auffinden verbesserter und neuer Enzyme
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Niehaus, Frank (Corresponding author)
Blanusa, Milan
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
An electrochemical microtiter plate for parallel spectroelectrochemical measurements
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Blanusa, Milan
Eck, Jürgen
Niehaus, Frank
Schwaneberg, Ulrich

[Patent]
A novel glucose oxidase, 2012

Schwaneberg, Ulrich
Prodanovic, Radivoje
Ostafe, Raluca
Niehaus, Frank
Eck, Jürgen

[Patent]
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Schwaneberg, Ulrich
Marienhagen, Jan
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Flow Cytometer-Based High-Throughput Screening System for Accelerated Directed Evolution of P450 Monooxygenases
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Blanusa, Milan
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
The role of active-site Phe87 in modulating the organic co-solvent tolerance of cytochrome P450 BM3 monooxygenase
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MuteinDB : the mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes
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Vanadium bromoperoxidase-coupled fluorescent assay for flow cytometry sorting of glucose oxidase gene libraries in double emulsions
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Prodanovic, Radivoje
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Blanusa, Milan
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Reengineering CelA2 cellulase for hydrolysis in aqueous solutions of deep eutectic solvents and concentrated seawater
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A rhodium complex-linked β-barrel protein as a hybrid biocatalyst for phenylacetylene polymerization
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MAP2.03D: A Sequence/Structure Based Server for Protein Engineering
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[Fachzeitschriftenartikel]
Directed Evolution of P 450 BM 3 into a p-Xylene Hydroxylase
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Ruff, Anna Joëlle
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[Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
dRTP and dPTP a complementary nucleotide couple for the Sequence Saturation Mutagenesis (SeSaM) method
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Fluorescent assay for directed evolution of perhydrolases
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Phosphorothioate-based DNA recombination: an enzyme-free method for the combinatorial assembly of multiple DNA fragments
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Dennig, Alexander
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[Fachzeitschriftenartikel]
Whos who? allocation of carbonyl reductase isoenzymes from candida parapsilosis by combining bio- and computational chemistry
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Directed evolution of subtilisin e into a highly active and guanidinium chloride- and sodium dodecylsulfate-tolerant protease
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Li, Zhenwei
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Lorenz, Michael
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
An efficient transformation method for Bacillus subtilis DB104
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Vojcic, Ljubica
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Maurer, Karl-Heinz
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Biocatalytic hydroxylation of n-butane with in situ cofactor regeneration at low temperature and under normal pressure
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First Insights on Organic Cosolvent Effects on FhuA Wildtype and FhuA Δ1-159
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Tenne, Stefanie-Joana
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Directed evolution of a highly active Yersinia mollaretii phytase
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[Fachzeitschriftenartikel]
Polymersome surface decoration by an EGFP fusion protein employing Cecropin A as peptide "anchor"
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[Fachzeitschriftenartikel]
Residue K556-A Light Triggerable Gatekeeper to Sterically Control Translocation in FhuA
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Güven, Arcan
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Fioroni, Marco
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
OmniChange: The Sequence Independent Method for Simultaneous Site-Saturation of Five Codons
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Shivange, Amol V.
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Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Electrochemical Oxidation of Glucose Using Mutant Glucose Oxidase from Directed Protein Evolution for Biosensor and Biofuel Cell Applications
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Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Schaltbare Proteine für interaktive Materialien
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Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates
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SeSaM-Tv-II Generates a Protein Sequence Space that is Unobtainable by epPCR
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First steps towards a Zn/Co(III)sep-driven P450 BM3 reactor
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Zhao, Liqing
Güven, Güray
Li, Yin
Schwaneberg, Ulrich

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Temperature effects on structure and dynamics of the psychrophilic protease subtilisin S41 and its thermostable mutants in solution
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Schwaneberg, Ulrich
Roccatano, Danilo

[Fachzeitschriftenartikel]
Directed evolution of a thermophilic endoglucanase (Cel5A) into highly active Cel5A variants with an expanded temperature profile
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Engineering of the E. coli outer membrane protein FhuA to overcome the hydrophobic mismatch in thick polymeric membranes
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Muhammad, Noor
Dworeck, Tamara
Fioroni, Marco (Corresponding author)
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Ultrahigh throughput screening system for directed glucose oxidase evolution in yeast cells
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Prodanovic, Radivoje
Ostafe, Raluca
Scacioc, Andreea
Schwaneberg, Ulrich

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A flow cytometry-based screening system for directed evolution of proteases
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Klein, Mathias Carsten
Schwaneberg, Ulrich

[Patent]
Directed evolution of Arginine Deiminase for increased activity at physiological PH, 2011

Schwaneberg, Ulrich
Zhu, Leilei

[Fachzeitschriftenartikel]
Nanocompartments with a pH release system based on an engineered OmpF channel protein
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Rapid evolution of arginine deiminase for improved anti-tumor activity
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[Fachzeitschriftenartikel]
FhuA deletion variant Δ1-159 overexpression in inclusion bodies and refolding with Polyethylene-Poly(ethylene glycol) diblock copolymer
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Dworeck, Tamara
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Muhammad, Noor
Fioroni, Marco
Schwaneberg, Ulrich

[Patent]
Method For The Enzymatic Reaction Of Alkanes, 2010

Gröger, Harald
Burda, Edyta
Schwaneberg, Ulrich
Marienhagen, Jan
Drauz, Karlheinz

[Patent]
Vesicles Comprising A Transmembrane Transport Trigger System, 2010

Schwaneberg, Ulrich
Onaca, Ozana
Sarkar, Prasenjit
Friedrich, Thomas
Hauer, Bernhard

[Fachzeitschriftenartikel]
Conformational dynamics of active site loop in Escherichia coli phytase
In: Biopolymers, 93 (11), 994-1002, 2010
[DOI: 10.1002/Bip.21513]

Shivange, Amol V.
Schwaneberg, Ulrich
Roccatano, Danilo

[Fachzeitschriftenartikel]
A Potential Antitumor Drug (Arginine Deiminase) Reengineered for Efficient Operation under Physiological Conditions
In: ChemBioChem, 11 (16), 2294-2301, 2010
[DOI: 10.1002/cbic.201000458]

Zhu, Leilei
Verma, Rajni
Roccatano, Danilo
Ni, Ye
Sun, Zhi-Hao
et al.

[Fachzeitschriftenartikel]
Directed Evolution of an Antitumor Drug (Arginine Deiminase PpADI) for Increased Activity at Physiological pH
In: ChemBioChem, 11 (5), 691-697, 2010
[DOI: 10.1002/cbic.200900717]

Zhu, Leilei
Tee, Kang Lan
Roccatano, Danilo
Sonmez, Burcu
Ni, Ye
et al.

[Fachzeitschriftenartikel]
Cloning, expression, and characterization of a thermostable glucoamylase from Thermoanaerobacter tengcongensis MB4
In: Applied microbiology and biotechnology, 87 (1), 225-233, 2010
[DOI: 10.1007/s00253-010-2439-0]

Zheng, Yingying
Xue, Yanfen
Zhang, Yueling
Zhou, Cheng
Schwaneberg, Ulrich
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[Fachzeitschriftenartikel]
Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450
In: Journal of lipid research : JLR, 51 (5), 1125-1133, 2010
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Lucas, Danièle
Goulitquer, Sophie
Marienhagen, Jan
Fer, Maude
Dreano, Yvonne
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[Fachzeitschriftenartikel]
Cloning and characterization of a thermostable and halo-tolerant endoglucanase from Thermoanaerobacter tengcongensis MB4
In: Applied microbiology and biotechnology, 89 (2), 315-326, 2010
[DOI: 10.1007/s00253-010-2842-6]

Liang, Chaoning
Xue, Yanfen
Fioroni, Marco
Rodriguez-Ropero, Francisco
Zhou, Cheng
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[Fachzeitschriftenartikel]
Rationalizing perhydrolase activity of aryl-esterase and subtilisin Carlsberg mutants by molecular dynamics simulations of the second tetrahedral intermediate state
In: Theoretical chemistry accounts, 125 (3/6), 375-386, 2010
[DOI: 10.1007/s00214-009-0611-3]

Lee, Wook
Vojcic, Ljubica
Despotovic, Dragana
Prodanovic, Radivoje
Maurer, Karl-Heinz
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[Fachzeitschriftenartikel]
Protein Engineering : an Option for Enzymatic Biofuel Cell Design
In: Electroanalysis, 22 (7/8), 765-775, 2010
[DOI: 10.1002/elan.200980017]

Güven, Güray
Prodanovic, Radivoje
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Molecular understanding of sterically controlled compound release through an engineered channel protein (FhuA)
In: Journal of nanobiotechnology, 8, 14, 2010
[DOI: 10.1186/1477-3155-8-14]

Güven, Arcan
Fioroni, Marco
Hauer, Bernhard
Schwaneberg, Ulrich (Corresponding author)

[Fachzeitschriftenartikel]
Mediated electron transfer with P450cin
In: Electrochemistry communications : EC, 12 (11), 1547-1550, 2010
[DOI: 10.1016/j.elecom.2010.08.030]

Çekiç, Sevil Zengin
Holtmann, Dirk
Güven, Güray
Mangold, Klaus-Michael
Schwaneberg, Ulrich
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[Fachzeitschriftenartikel]
Phosphorothioate-based ligase-independent gene cloning (PLICing): An enzyme-free and sequence-independent cloning method
In: Analytical biochemistry, 406 (2), 141-146, 2010
[DOI: 10.1016/J.Ab.2010.07.011]

Blanusa, Milan
Schenk, Alexander
Sadeghi, Hengameh
Marienhagen, Jan
Schwaneberg, Ulrich

[Patent]
Proteine mit Esterase-Aktivität, 2009

Breuer, Michael
Hauer, Bernhard
Schwaneberg, Ulrich
Wong, Tuck Seng

[Fachzeitschriftenartikel]
Applying metagenomics for the identification of bacterial cellulases that are stable in ionic liquids
In: Green chemistry : GC, 11 (7), 957-965, 2009
[DOI: 10.1039/B820157a]

Pottkämper, Julia
Barthen, Peter
Ilmberger, Nele
Schwaneberg, Ulrich
Schenk, Alexander
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[Fachzeitschriftenartikel]
Expression of Arginine Deiminase from Pseudomonas plecoglossicida CGMCC2039 in Escherichia coli and Its Anti-Tumor Activity
In: Current microbiology, 58 (6), 593-598, 2009
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Ni, Ye
Li, Zhenwei
Sun, Zhihao H.
Zheng, Pu
Liu, Yongmei M.
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[Fachzeitschriftenartikel]
Biochemie und Molekularbiologie 2008
In: Nachrichten aus der Chemie, 57 (3), 278-286, 2009
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Marienhagen, Jan
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Advances in generating functional diversity for directed protein evolution
In: Current opinion in chemical biology, 13 (1), 19-25, 2009
[DOI: 10.1016/j.cbpa.2009.01.019]

Shivange, Amol V.
Marienhagen, Jan
Mundhada, Hemanshu
Schenk, Alexander
Schwaneberg, Ulrich

[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Flow cytometry based high throughput screening system for screening and improving industrially important enzymes
In: New biotechnology, 25 (2), S144-S144, 2009
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Tu, R.
Prodanovic, Radivoje
Blanusa, M.
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Niehaus, Frank
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[Patent]
Neue Cytochrom P450-monooxygenasen und deren Verwendung zur Oxidation von Organischen Verbindungen, 2008

Hauer, Bernhard
Pleiss, Juergen
Schwaneberg, Ulrich
Flscher, Markus
Schmid, Rolf D.
et al.

[Patent]
A process for sequence Saturation mutagenesis (sesam), 2008

Schwaneberg, Ulrich

[Buchbeitrag, Beitrag zu einem Tagungsband]
Functional Polymerosomes (Synthosomes) for Bioconversions and Selective Product Recovery
In: Nanotechnology 2008 : technical proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Boston, June 1 - 5, 2008 ; NSTI Nanotech - the Nanotechnology Conference and Trade Show ; an interdisciplinary integrative forum on nanotechnology, biotechnology and microtechnology ; ... includes: 2008 NSTI Bio Nano Conference and Trade Show, Bio Nano 2008 - 11th International Conference on Modeling and Simulation of Microsystems, MSM 2008 - 8th International Conference on Computational Nanoscience and Technology, ICCN 2008 - 7th Workshop on Compact Modeling, WCM 2008 - NSTI Nanotech Ventures 2008 - 2008 TechConnect Summit - Clean Technology 2008 / Nano Science and Technology Institute. Proceedings ed.: Matthew Laudon; Bart Romanowicz, 325-327, 2008

Güven, Aybars
Ihle, Saskia
Fioroni, Marco
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Arginine deiminase, a potential anti-tumor drug
In: Cancer letters, 261 (1), 1-11, 2008
[DOI: 10.1016/j.canlet.2007.11.038]

Ni, Ye
Schwaneberg, Ulrich
Sun, Zhi-Hao

[Fachzeitschriftenartikel]
Laboratory evolution of P450 BM3 for mediated electron transfer yielding an activity-improved and reductase-independent variant
In: Protein engineering design & selection : peds, 21 (1), 29-35, 2008
[DOI: 10.1093/protein/gzm074]

Nazor, Jovana
Dannenmann, Stephanie
Adjei, Richard Obeng
Fordjour, Yaw Boafo
Ghampson, Isaac T.
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[Fachzeitschriftenartikel]
Transversion-enriched sequence saturation mutagenesis (SeSaM-Tv+): a random mutagenesis method with consecutive nucleotide exchanges that complements the bias of error-prone PCR
In: Biotechnology journal : BTJ, 3 (1), 74-82, 2008
[DOI: 10.1002/biot.200700193]

Wong, Tuck Seng
Roccatano, Danilo
Loakes, David
Tee, Kang Lan
Schenk, Alexander
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[Fachzeitschriftenartikel]
Functionalized Nanocompartments (Synthosomes) with a Reduction-Triggered Release System
In: Angewandte Chemie / International edition, 47 (37), 7029-7031, 2008
[DOI: 10.1002/anie.200801076]

Onaca, Ozana
Sarkar, Pransenjit
Roccatano, Danilo
Friedrich, Thomas
Hauer, Bernhard
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[Fachzeitschriftenartikel]
Ionic liquid effects on the activity of monooxygenase P450 BM-3
In: Green chemistry : GC, 10 (1), 117-123, 2008
[DOI: 10.1039/B714674d]

Tee, Kang Lan
Roccatano, Danilo
Stolte, Stefan
Arning, Jürgen
Jastorff, Bernd
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[Buchbeitrag, Fachzeitschriftenartikel]
A p-nitrothiophenolate screening system for the directed evolution of a two-component epoxygenase (StyAB)
In: Journal of molecular catalysis / B, Enzymatic, 50 (2/4), 121-127, 2008
[DOI: 10.1016/j.molcatb.2007.09.008]

Tee, Kang Lan
Dmytrenko, Olrg
Otto, Katja
Schmid, Andreas
Schwaneberg, Ulrich

[Patent]
Cytochrom P450 Oxygenases, 2007

Farinas, Edgardo T.
Arnold, Frances H.
Schwaneberg, Ulrich
Glieder, Anton

[Patent]
Modifizierte Cytochrom P450-monooxygenasen, 2007

Hauer, Bernhard
Pleiss, Juergen
Schwaneberg, Ulrich
Schmitt, Jutta
Fischer, Markus
et al.

[Fachzeitschriftenartikel]
Directed evolution of oxygenases : screening systems, success stories and challenges
In: Combinatorial chemistry & high throughput screening, 10 (3), 197-217, 2007
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Tee, K. L.
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Understanding a mechanism of organic cosolvent inactivation in heme monooxygenase P450 BM-3
In: Journal of the American Chemical Society : JACS, 129 (18), 5786-5787, 2007
[DOI: 10.1021/ja067036x]

Kuper, Jochen
Wong, Tuck Seng
Roccatano, Danilo
Wilmanns, Matthias
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Directed evolution of glucose oxidase from Aspergillus niger for ferrocenemethanol-mediated electron transfer
In: Biotechnology journal : BTJ, 2 (2), 241-248, 2007
[DOI: 10.1002/biot.200600185]

Zhu, Ziwei W.
Wang, Mian
Gautam, Amit
Nazor, Jovana
Momeu, Carmen
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[Fachzeitschriftenartikel]
Steering directed protein evolution: strategies to manage combinatorial complexity of mutant libraries
In: Environmental microbiology, 9 (11), 2645-2659, 2007
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Wong, T. S.
Roccatano, D.
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Challenges of the genetic code for exploring sequence space in directed protein evolution
In: Biocatalysis and biotransformation, 25 (2/4), 229-241, 2007
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Wong, T. S.
Roccatano, D.
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Are transversion mutations better? A Mutagenesis Assistant Program analysis on P450 BM-3 heme domain
In: Biotechnology journal : BTJ, 2 (1), 133-142, 2007
[DOI: 10.1002/biot.200600201]

Wong, Tuck Seng
Roccatano, Danilo
Schwaneberg, Ulrich

[Patent]
Elektronendonorsystem für Enzyme und dessen Anwendung bei der biochemischen Umsetzung von Substraten, 2006

Hauer, Bernhard
Schmid, Rolf D.
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
SeSaM (Sequence Saturation Mutagenesis) : eine Methode zur Sättigungsmutagenese eines Genes
In: Biospektrum : das Magazin für Biowissenschaften, 3, 277-279, 2006

Schenk, Alexander
Wong, Tuck Seng
Roccatano, Danilo
Hauer, Bernhard
Schwaneberg, Ulrich

[Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Gelenkte Evolution von Epoxygenasen
In: Chemie - Ingenieur - Technik, 78 (9), 1438-1439, 2006
[DOI: 10.1002/cite.200650443]

Tee, K. L.
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
A nanophosphor-based method for selective DNA recovery in Synthosomes
In: Biotechnology journal : BTJ, 1 (7/8), 828-834, 2006
[DOI: 10.1002/biot.200600042]

Nallani, Madhavan
Onaca, Ozana
Gera, Nimish
Hildenbrand, Karlheinz
Hoheisel, Werner
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[Fachzeitschriftenartikel]
A nanocompartment system (Synthosome) designed for biotechnological applications
In: Journal of biotechnology, 123 (1), 50-59, 2006
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Nallani, Madhavan
Benito, Samantha
Onaca, Ozana
Graff, Alexandra
Lindemann, Marcus
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[Fachzeitschriftenartikel]
A Statistical Analysis of Random Mutagenesis Methods Used for Directed Protein Evolution
In: Journal of molecular biology, 355 (4), 858-871, 2006
[DOI: 10.1016/j.jmb.2005.10.082]

Wong, Tuck Seng
Roccatano, Danilo
Zacharias, Martin
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
A Screening System for the Directed Evolution of Epoxygenases: Importance of Position 184 in P450 BM3 for Stereoselective Styrene Epoxidation
In: Angewandte Chemie / International edition, 45 (32), 5380-5383, 2006
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Tee, Kang Lan
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Laboratory evolution of P450 BM-3 for mediated electron transfer
In: ChemBioChem, 7 (4), 638-644, 2006
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Nazor, Jovana
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Functionalized nanocompartments (Synthosomes): limitations and prospective applications in industrial biotechnology
In: Biotechnology journal : BTJ, 1 (7/8), 795-805, 2006
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Onaca, Ozana
Nallani, Madhavan
Ihle, Saskia
Schenk, Alexander
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Toward understanding the inactivation mechanism of monooxygenase P450 BM-3 by organic cosolvents: a molecular dynamics simulation study
In: Biopolymers, 83 (5), 467-476, 2006
[DOI: 10.1002/bip.20577]

Roccatano, Danilo
Wong, Tuck Seng
Schwaneberg, Ulrich
Zacharias, Martin

[Fachzeitschriftenartikel]
Making glucose oxidase fit for biofuel cell applications by directed protein evolution
In: Biosensors and bioelectronics, 21 (11), 2046-2051, 2006
[DOI: 10.1016/j.bios.2005.11.018]

Zhu, Ziwei W.
Momeu, Carmen
Zakhartsev, Maxim
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
The diversity challenge in directed protein evolution
In: Combinatorial chemistry & high throughput screening, 9 (4), 271-288, 2006
[DOI: 10.2174/138620706776843192]

Wong, Tuck S.
Zhurina, Daria
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
A filter paper-based assay for laboratory evolution of hydrolases and dehydrogenases
In: Combinatorial chemistry & high throughput screening, 9 (4), 289-293, 2006
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Wong, Tuck S.
Schwaneberg, Ulrich
Sturmer, Rainer
Hauer, Bernhard
Breuer, Michael

[Patent]
Vesicle Used To Separate Substances From Liquid Media, 2006

Meier, Wolfgang
Schwaneberg, Ulrich
Winterhalter, Mathias

[Fachzeitschriftenartikel]
Structural and dynamic properties of cytochrome P450 BM-3 in pure water and in a dimethylsulfoxide/water mixture
In: Biopolymers, 78 (5), 259-267, 2005
[DOI: 10.1002/bip.20290]

Roccatano, Danilo
Wong, Tuck Seng
Schwaneberg, Ulrich
Zacharias, Martin

[Fachzeitschriftenartikel]
Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds
In: Journal of biomolecular screening, 10 (3), 246-252, 2005
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Wong, T. S.
Wu, N.
Roccatano, D.
Zacharias, M.
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Sequence saturation mutagenesis with tunable mutation frequencies
In: Analytical biochemistry, 341 (1), 187-189, 2005
[DOI: 10.1016/j.ab.2005.03.023]

Wong, Tuck Seng
Tee, Kang Lan
Hauer, Bernhard
Schwaneberg, Ulrich

[Abstract, Fachzeitschriftenartikel]
Substrate translocation through porin
In: Biophysical journal : BJ, 88 (Abstracts issue), 584a-584a, 2005

Mach, T.
Neves, P.
Ganeva, V.
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[Fachzeitschriftenartikel]
Laboratory evolution of cytochrome P450 BM-3 monooxygenase for organic cosolvents
In: Biotechnology and bioengineering, 85 (3), 351-358, 2004
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Wong, Tuck Seng
Arnold, Frances H.
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution
In: Nucleic acids research, 32 (3), e26-e26, 2004
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Wong, Tuck Seng
Tee, Kang Lan
Hauer, Berhard
Schwaneberg, Ulrich

[Patent]
Screening Method For The Discovery And Directed Evolution Of Oxygenase Enzymes, 2003

Arnold, Frances H.
Joern, John
Sakamoto, Takeshi
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Protein engineering in bioelectrocatalysis
In: Current opinion in biotechnology, 14 (6), 590-696, 2003
[DOI: 10.1016/j.copbio.2003.09.008]

Wong, Tuck Seng
Schwaneberg, Ulrich

[Patent]
Neue Cytochrom P450-Monooxygenasen und deren Verwendung zur Oxidation N-heterocyclischer Aromaten, 2001

Hauer, Bernhard
Pleiss, Juergen
Schwaneberg, Ulrich
Schmitt, Jutta
Fischer, Markus
et al.

[Fachzeitschriftenartikel]
Rational evolution of a medium chain-specific cytochrome P-450 BM-3 variant
In: Biochimica et biophysica acta : BBA / Proteins and Proteomics, 1545 (1/2), 114-121, 2001
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Li, Q. S.
Schwaneberg, Ulrich
Fischer, M.
Schmitt, J.
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[Fachzeitschriftenartikel]
A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes
In: Journal of biotechnology, 88 (2), 167-171, 2001
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Appel, Daniel
Lutz-Wahl, Sabine
Fischer, Peter
Schwaneberg, Ulrich
Schmid, Rolf D.

[Buchbeitrag, Fachzeitschriftenartikel]
Directed evolution of a cytochrome P450 monooxygenase for alkane oxidation
In: Advanced synthesis & catalysis, 343 (6/7), 601-606, 2001
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Farinas, E. T.
Schwaneberg, Ulrich
Glieder, A.
Arnold, Frances H.

[Fachzeitschriftenartikel]
Modification of the fatty acid specificity of cytochrome P450BM-3 from Bacillus megaterium by directed evolution: A validated assay
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Lentz, O.
Qing-Shang, L. I.
Schwaneberg, Ulrich
Lutz-Wahl, S.
Fischer, P.
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[Fachzeitschriftenartikel]
Cost-effective whole-cell assay for laboratory evolution of hydroxylases in Escherichia coli
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Schwaneberg, Ulrich
Otey, C.
Cirino, P. C.
Farinas, E.
Arnold, Frances H.

[Patent]
Elektronendonorsystem für Enzyme, 2001

Hauer, Bernhard
Schmid, Rolf D.
Schwaneberg, Ulrich

[Fachzeitschriftenartikel]
Directed evolution of the fatty-acid hydyoxylase P450BM-3 into an indole-hydroxylating catalyst
In: Chemistry : a European journal, 6 (9), 1531-1536, 2000
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Li, Q. S.
Schwaneberg, Ulrich
Fischer, P.
Schmid, R. D.

[Fachzeitschriftenartikel]
P450 in biotechnology : zinc driven ω-hydroxylation of p-nitrophenoxydodecanoic acid using P450 BM-3 F87A as a catalyst
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Schwaneberg, Ulrich
Appel, Daniel
Schmitt, Jutta
Schmid, Rolf D.

[Fachzeitschriftenartikel]
A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A
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Schwaneberg, Ulrich
Schmidt-Dannert, C.
Schmitt, J.
Schmid, R. D.

[Fachzeitschriftenartikel]
P450 monooxygenase in biotechnology - I. Single-step, large-scale purification method for cytochrome P450BM-3 by anion-exchange chromatography
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Schmidt-Dannert, C.
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[Fachzeitschriftenartikel]
Expression of the Zn2+-containing hydroxynitrile lyase from flax (Linum usitatissimum) in Pichia pastoris - utilization of the recombinant enzyme for enzymatic analysis and site-directed mutagenesis
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Chemoenzymatic route to β-blockers via 3-hydroxy esters
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[Fachzeitschriftenartikel]
Prearranged glycosides, 2. Intramolecular glycosylation of prearranged saccharides as a novel strategy for the construction of β-L-rhamnosidic linkages
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