Next Generation Biocatalysis

  Scheme highlighting the NGBC research activities Copyright: © Biotec

The division Next Generation Biocatalysis, short for NGBC, aims to develop new enzymatic reactions or reaction cascades, methods and technologies to overcome the limitations of aqueous biotransformations. By dissolving the strict barriers between chemical and biological catalysis worlds, the flexibility of chemical catalysts and the selectivity of enzymes could be combined in a unique way. A second, central focus of our research lies in the implementation of engineered biocatalysts in microbial chassis to enable biosynthesis routes towards valuable plant secondary metabolites. A key aspect of our research is the development of new or the improvement of established stereoselective biotransformations.

To meet this objective, our research combines the cross-cutting topics of directed enzyme evolution, bio-(hybrid) catalysis, and organic chemistry, which nicely ties the core competences of the Schwaneberg group. The interdisciplinary approach pursued by the NGBC division harnesses the expertise of trained molecular and synthetic biologists, material scientists, and chemists. The NGBC division is headed by Dr. Johannes Schiffels.

Here you’ll find information about the NGBC group members.

Here you’ll find comprehensive information about the current research activities of the division Next Generation Biocatalysis.

Specifically, the following positions for Bachelor- or Master Theses are available:

Directed Evolution of a decarboxylase (Master-/Bachelor Thesis or Internship)

Whole-cell biocatalysis in organic solvents (Master-/Bachelor Thesis or Internship)

Recombinant Production and characterization of novel carotenoid-cleaving enzymes within the saffron biosynthetic pathway (Master-/Bachelor Thesis)


Have we caught your interest?

We are always looking for highly motivated bachelor or master students who are interested in doing their thesis or internship within the interdisciplinary field of catalysis. If you want to join our team, please contact us.